Reply to "Vancomycin-induced nephrotoxicity".
نویسندگان
چکیده
S. J. van Hal, D. L. Paterson, T. P. Lodise Department of Microbiology & Infectious Diseases, Royal Prince Alfred Hospital, Sydney, Australia; Antibiotic Resistance & Mobile Elements Group, Microbiology and Infectious Diseases Unit, School of Medicine, University of Western Sydney, Sydney, Australia; University of Queensland Centre for Clinical Research (UQCCR), Herston, Australia; Albany College of Pharmacy and Health Sciences, Albany, New York, USA
منابع مشابه
Elevated Vancomycin Trough Concentration: Increased Efficacy and/or Toxicity?
Vancomycin susceptibility of methicillin-resistant Staphylococcus aureus has been changed over time and its average minimum inhibitory concentration increased from 1.5 to 1.75 mg/L. A recently published guideline by the American Society of Health Pharmacist recommended a daily dose of 15-20 mg/kg every 8 to 12 hours of vancomycin to achieve a trough concentration between 15-20 mg/L for treatmen...
متن کاملElevated Vancomycin Trough Concentration: Increased Efficacy and/or Toxicity?
Vancomycin susceptibility of methicillin-resistant Staphylococcus aureus has been changed over time and its average minimum inhibitory concentration increased from 1.5 to 1.75 mg/L. A recently published guideline by the American Society of Health Pharmacist recommended a daily dose of 15-20 mg/kg every 8 to 12 hours of vancomycin to achieve a trough concentration between 15-20 mg/L for treatmen...
متن کاملSystematic review and meta-analysis of vancomycin-induced nephrotoxicity associated with dosing schedules that maintain troughs between 15 and 20 milligrams per liter.
In an effort to maximize outcomes, recent expert guidelines recommend more-intensive vancomycin dosing schedules to maintain vancomycin troughs between 15 and 20 mg/liter. The widespread use of these more-intensive regimens has been associated with an increase in vancomycin-induced nephrotoxicity reports. The purpose of this systematic literature review is to determine the nephrotoxicity potent...
متن کاملA SILAC-Based Approach Elicits the Proteomic Responses to Vancomycin-Associated Nephrotoxicity in Human Proximal Tubule Epithelial HK-2 Cells.
Vancomycin, a widely used antibiotic, often induces nephrotoxicity, however, the molecular targets and underlying mechanisms of this side effect remain unclear. The present study aimed to examine molecular interactome and analyze the signaling pathways related to the vancomycin-induced nephrotoxicity in human proximal tubule epithelial HK-2 cells using the stable isotope labeling by amino acids...
متن کاملVancomycin-induced acute tubular necrosis.
OBJECTIVES To report nephrotoxicity in the form of acute tubular necrosis (ATN) related to vancomycin. METHODS This study was conducted at Johns Hopkins Aramco Healthcare, Saudi Aramco, Dharan, Saudi Arabia between June and August 2013. All patients who received intravenous vancomycin as a part of the hospital's vancomycin stewardship program were monitored for the development of ATN. RESUL...
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 57 5 شماره
صفحات -
تاریخ انتشار 2013